I'm running one with my car and it works very well (Hellion kit, 62mm turbo, 47lb injectors, 340lb/hr fuel pump). The dyno shop I work with is very familiar with megasquirts and had no trouble with it. I've played with tuning it a bit myself as well and found it quite easy to use generally. Some of the settings to get it to idle well are a bit tricky but other than that it was pretty painless.
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