Depends. If you have it close to stock ride hight, its probably going to be fine. Lower it much, without the fender being rolled, and it (the fender) will cut the tire. You could probably get away with lowering it if its not driven much.
Its pretty easy to roll or cut the fender though.
I predict future happiness for Americans if they can prevent the government from wasting the labors of the people under the pretense of taking care of them. -